Hepacept®

Resveratrol, Curcumin, Boswellia and Green tea catechins were reviewed as natural immunomodulators with an excellent safety profile and a promising potential for treating inflammations, such as IBD (inflammatory bowel disease).

Clarke JO, Mullin GE.
A review of complementary and alternative approaches to immunomodulation.

http://www.ncbi.nlm.nih.gov/Abstract

Aggarwal BB, Kumar A, Bharti AC.
Anticancer potential of curcumin: preclinical and clinical studies.

http://www.ncbi.nlm.nih.gov/uids=12680238&dopt=Abstract

Ammon HP.
Boswellic acids (components of frankincense) as the active principle in treatment of chronic inflammatory diseases

http://www.ncbi.nlm.nih.gov/uids=12244881&dopt=Abstract

Ammon HP, Safayhi H, Mack T, Sabieraj J.
Mechanism of antiinflammatory actions of curcumine and boswellic acids.

http://www.ncbi.nlm.nih.gov/uids=8510458&dopt=Abstract

Ammon HP, Wahl MA.
Pharmacology of Curcuma longa.

http://www.ncbi.nlm.nih.gov/uids=2062949&dopt=Abstract

Araujo CC, Leon LL.
Biological activities of Curcuma longa L.

http://www.ncbi.nlm.nih.gov/uids=11500779&dopt=Abstract

Atal CK, Zutshi U, Rao PG.
Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs.

http://www.ncbi.nlm.nih.gov/uids=7311598&dopt=Abstract

Atal CK, Dubey RK, Singh J.
Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism.

http://www.ncbi.nlm.nih.gov/uids=73917507&dopt=Abstract

Auger C, Teissedre PL, Gerain P, Lequeux N, Bornet A, Serisier S, Besancon P, Caporiccio B, Cristol JP, Rouanet JM.
Dietary wine phenolics catechin, quercetin, and resveratrol efficiently protect hypercholesterolemic hamsters against aortic fatty streak accumulation.

http://www.ncbi.nlm.nih.gov/uids=15769129&dopt=Abstract

Azmi AS, Bhat SH, Hadi SM.
Resveratrol-Cu(II) induced DNA breakage in human peripheral lymphocytes: Implications for anticancer properties.

http://www.ncbi.nlm.nih.gov/uids=15919081&dopt=Abstract

Bean P.
The use of alternative medicine in the treatment of hepatitis C.

http://www.ncbi.nlm.nih.gov/uids=12087634&dopt=Abstract

Busquets S, Ametller E, Fuster G, Olivan M, Raab V, Argiles JM, Lopez-Soriano FJ.
Resveratrol, a natural diphenol, reduces metastatic growth in an experimental cancer model.

http://www.ncbi.nlm.nih.gov/Abstract

Cha TL, Qiu L, Chen CT, Wen Y, Hung MC.
Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth.

http://www.ncbi.nlm.nih.gov/uids=15781642&dopt=Abstract

Chainani-Wu N.
Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa).

http://www.ncbi.nlm.nih.gov/uids=12676044&dopt=Abstract

Delmas D, Jannin B, Latruffe N.
Resveratrol: preventing properties against vascular alterations and ageing.

http://www.ncbi.nlm.nih.gov/Abstract

Das DK, Maulik N.
Resveratrol in cardioprotection: a therapeutic promise of alternative medicine.

http://www.ncbi.nlm.nih.gov/Abstract

Duvoix A, Blasius R, Delhalle S, Schnekenburger M, Morceau F, Henry E, Dicato M, Diederich M.
Chemopreventive and therapeutic effects of curcumin.

http://www.ncbi.nlm.nih.gov/uids=15896452&dopt=Abstract

Elmali N, Esenkaya I, Harma A, Ertem K, Turkoz Y, Mizrak B.
Effect of resveratrol in experimental osteoarthritis in rabbits.

http://www.ncbi.nlm.nih.gov/uids=15883738&dopt=Abstract

Ferenci P, Dragosics B, Dittrich H, Frank H, Benda L, Lochs H, Meryn S, Base W, Schneider B.
Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver.

http://www.ncbi.nlm.nih.gov/uids=2671116&dopt=Abstract

Flora K, Hahn M, Rosen H, Benner K.
Milk thistle (Silybum marianum) for the therapy of liver disease.

http://www.ncbi.nlm.nih.gov/uids=9468229&dopt=Abstract

Fremont L.
Biological effects of resveratrol.

http://www.ncbi.nlm.nih.gov/uids=10680575&dopt=Abstract

Garcea G, Berry DP, Jones DJ, Singh R, Dennison AR, Farmer PB, Sharma RA, Steward WP, Gescher AJ.
Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences.

http://www.ncbi.nlm.nih.gov/uids=15668484&dopt=Abstract

Garvin S, Ollinger K, Dabrosin C.
Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo.

http://www.ncbi.nlm.nih.gov/Abstract

Huang MT, Badmaev V, Ding Y, Liu Y, Xie JG, Ho CT.
Anti-tumor and anti-carcinogenic activities of triterpenoid, beta-boswellic acid.

http://www.ncbi.nlm.nih.gov/uids=11237186&dopt=Abstract

Igura K, Ohta T, Kuroda Y, Kaji K.
Resveratrol and quercetin inhibit angiogenesis in vitro.

http://www.ncbi.nlm.nih.gov/uids=11485823&dopt=Abstract

Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM.
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes.

http://www.ncbi.nlm.nih.gov/uids=8985016&dopt=Abstract

Jing XB, Ueki N, Cheng JD, Imanishi H, Hada T
Induction of apoptosis in hepatocellular carcinoma cell lines by emodin

http://www.ncbi.nlm.nih.gov/uids=12716464&dopt=Abstract

Johri RK, Zutshi U.
An Ayurvedic formulation 'Trikatu' and its constituents.

http://www.ncbi.nlm.nih.gov/uids=1434692&dopt=Abstract

Kang HC, Nan JX, Park PH, Kim JY, Lee SH, Woo SW, Zhao YZ, Park EJ, Sohn DH.
Curcumin inhibits collagen synthesis and hepatic stellate cell activation in-vivo and in-vitro.

http://www.ncbi.nlm.nih.gov/uids=11829122&dopt=Abstract

Kren V, Walterova D.
Silybin and silymarin - new effects and applications.

http://www.ncbi.nlm.nih.gov/Abstract

Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B.
Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study.

http://www.ncbi.nlm.nih.gov/uids=1943180&dopt=Abstract

Lieber CS, Leo MA, Cao Q, Ren C, DeCarli LM.
Silymarin retards the progression of alcohol-induced hepatic fibrosis in baboons.

http://www.ncbi.nlm.nih.gov/uids=14506392&dopt=Abstract

Lukita-Atmadja W, Ito Y, Baker GL, McCuskey RS.
Effect of curcuminoids as anti-inflammatory agents on the hepatic microvascular response to endotoxin.

http://www.ncbi.nlm.nih.gov/uids=12022761&dopt=Abstract

Madisch A, Miehlke S, Eichele O, Mrwa J, Bethke B, Kuhlisch E, Bästlein E, Wilhelms G, Morgner A, Wigginghaus B, Stolte M.
Boswellia serrata extract for the treatment of collagenous colitis. A double-blind, randomized, placebo-controlled, multicenter trial.

http://www.ncbi.nlm.nih.gov/&dopt=Abstract

Marambaud P, Zhao H, Davies P.
Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

http://www.ncbi.nlm.nih.gov/Abstract

Martin AR, Villegas I, Sanchez-Hidalgo M, de la Lastra CA.
The effects of resveratrol, a phytoalexin derived from red wines, on chronic inflammation induced in an experimentally induced colitis model.

http://www.ncbi.nlm.nih.gov/Abstract

Miatello R, Vazquez M, Renna N, Cruzado M, Zumino AP, Risler N.
Chronic administration of resveratrol prevents biochemical cardiovascular changes in fructose-fed rats.

http://www.ncbi.nlm.nih.gov/uids=15925749&dopt=Abstract

Olas B, Wachowicz B, Majsterek I, Blasiak J.
Resveratrol may reduce oxidative stress induced by platinum compounds in human plasma, blood platelets and lymphocytes.

http://www.ncbi.nlm.nih.gov/uids=15930895&dopt=Abstract

Palamara AT, Nencioni L, Aquilano K, De Chiara G, Hernandez L, Cozzolino F, Ciriolo MR, Garaci E.
Inhibition of influenza a virus replication by resveratrol.

http://www.ncbi.nlm.nih.gov/uids=15838800&dopt=Abstract

Paul B, Masih I, Deopujari J, Charpentier C.
Occurrence of resveratrol and pterostilbene in age-old darakchasava, an ayurvedic medicine from India.

http://www.ncbi.nlm.nih.gov/uids=10624864&dopt=Abstract

Prucksunand C, Indrasukhsri B, Leethochawalit M, Hungspreugs K.
Phase II clinical trial on effect of the long turmeric (Curcuma longa Linn) on healing of peptic ulcer.

http://www.ncbi.nlm.nih.gov/uids=11485087&dopt=Abstract

Ramsewak RS, DeWitt DL, Nair MG.
Cytotoxicity, antioxidant and anti-inflammatory activities of curcumins I-III from Curcuma longa.

http://www.ncbi.nlm.nih.gov/uids=10969724&dopt=Abstract

Rasyid A, Rahman AR, Jaalam K, Lelo A.
Effect of different curcumin dosages on human gall bladder.

http://www.ncbi.nlm.nih.gov/uids=12495265&dopt=Abstract

Saller R, Meier R, Brignoli R.
The use of silymarin in the treatment of liver diseases.

http://www.ncbi.nlm.nih.gov/uids=11735632&dopt=Abstract

Salmi HA, Sarna S.
Effect of silymarin on chemical, functional, and morphological alterations of the liver. A double-blind controlled study.

http://www.ncbi.nlm.nih.gov/uids=6753109&dopt=Abstract

Sharma RA, McLelland HR, Hill KA, Ireson CR, Euden SA, Manson MM, Pirmohamed M, Marnett LJ, Gescher AJ, Steward WP.
Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.

http://www.ncbi.nlm.nih.gov/uids=11448902&dopt=Abstract

Shishodia S, Sethi G, Aggarwal BB.
Curcumin: getting back to the roots.

http://www.ncbi.nlm.nih.gov/Abstract

Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS.
Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers.

http://www.ncbi.nlm.nih.gov/uids=9619120&dopt=Abstract

Shoskes D, Lapierre C, Cruz-Corerra M, Muruve N, Rosario R, Fromkin B, Braun M, Copley J.
Beneficial effects of the bioflavonoids curcumin and quercetin on early function in cadaveric renal transplantation: a randomized placebo controlled trial.

http://www.ncbi.nlm.nih.gov/Abstract

Sovak M.
Grape Extract, Resveratrol, and Its Analogs: A Review.

http://www.ncbi.nlm.nih.gov/uids=12639418&dopt=Abstract

van Loon IM.
The golden root: Clinical applications of Scutellaria baicalensis Georgi. Flavonoids as modulators of the inflammatory response

http://www.thorne.com/altmedrev/fulltext/scutellaria2-6.html

Wellington K, Jarvis B.
Silymarin: a review of its clinical properties in the management of hepatic disorders.

http://www.ncbi.nlm.nih.gov/uids=11520257&dopt=Abstract

Zhou HB, Chen JJ, Wang WX, Cai JT, Du Q.
Anticancer activity of resveratrol on implanted human primary gastric carcinoma cells in nude mice.

http://www.ncbi.nlm.nih.gov/uids=15633232&dopt=Abstract

Zihua Gong; Yaozog Yuan; Kaixian Lou; Shuiping Tu; Zukang Zhai; Jiayu Xu
Mechanisms of Chinese Herb Emodin and Somatostatin Analogs on Pancreatic Regeneration in Acute Pancreatitis in Rats

http://www.ncbi.nlm.nih.gov/uids=12142738&dopt=Abstract

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