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Resveratrol, Curcumin, Boswellia and Green tea catechins were reviewed as natural immunomodulators with an excellent safety profile and a promising potential for treating inflammations, such as IBD (inflammatory bowel disease).

Clarke JO, Mullin GE.
A review of complementary and alternative approaches to immunomodulation.

http://www.ncbi.nlm.nih.gov/Abstract

Aggarwal BB, Shishodia S, Takada Y, Banerjee S, Newman RA, Bueso-Ramos CE, Price JE.
Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.

http://www.ncbi.nlm.nih.gov/Abstract

Auger C, Teissedre PL, Gerain P, Lequeux N, Bornet A, Serisier S, Besancon P, Caporiccio B, Cristol JP, Rouanet JM.
Dietary wine phenolics catechin, quercetin, and resveratrol efficiently protect hypercholesterolemic hamsters against aortic fatty streak accumulation.

http://www.ncbi.nlm.nih.gov/uids=15769129&dopt=Abstract

Azmi AS, Bhat SH, Hadi SM.
Resveratrol-Cu(II) induced DNA breakage in human peripheral lymphocytes: Implications for anticancer properties.

http://www.ncbi.nlm.nih.gov/uids=15919081&dopt=Abstract

Busquets S, Ametller E, Fuster G, Olivan M, Raab V, Argiles JM, Lopez-Soriano FJ.
Resveratrol, a natural diphenol, reduces metastatic growth in an experimental cancer model.

http://www.ncbi.nlm.nih.gov/Abstract

Cha TL, Qiu L, Chen CT, Wen Y, Hung MC.
Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth.

http://www.ncbi.nlm.nih.gov/uids=15781642dopt=Abstract

Chauhan DP.
Chemotherapeutic potential of curcumin for colorectal cancer.

http://www.ncbi.nlm.nih.gov/uids=12171541&dopt=Abstract

Cheng AL, Hsu CH, Lin JK, Hsu MM, Ho YF, et al.
Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions.

http://www.ncbi.nlm.nih.gov/uids=11712783

Corder R, Douthwaite JA, Lees DM, Khan NQ, Viseu Dos Santos AC, Wood EG, Carrier MJ.
Endothelin-1 synthesis reduced by red wine.

http://www.ncbi.nlm.nih.gov/uids=11780050&dopt=Abstract

Das DK, Maulik N.
Resveratrol in cardioprotection: a therapeutic promise of alternative medicine.

http://www.ncbi.nlm.nih.gov/Abstract

Delmas D, Jannin B, Latruffe N.
Resveratrol: preventing properties against vascular alterations and ageing.

http://www.ncbi.nlm.nih.gov/Abstract

Dorai T, Aggarwal BB.
Role of chemopreventive agents in cancer therapy.

http://www.ncbi.nlm.nih.gov/Abstract

Dorai T, Cao YC, Dorai B, Buttyan R, Katz AE.
Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo.

http://www.ncbi.nlm.nih.gov/uids=11398177&dopt=Abstract

Elmali N, Esenkaya I, Harma A, Ertem K, Turkoz Y, Mizrak B.
Effect of resveratrol in experimental osteoarthritis in rabbits.

http://www.ncbi.nlm.nih.gov/uids=15883738&dopt=Abstract

Folts JD.
Potential health benefits from the flavonoids in grape products on vascular disease.

http://www.ncbi.nlm.nih.gov/Abstract

Fremont L.
Biological effects of resveratrol.

http://www.ncbi.nlm.nih.gov/uids=10680575&dopt=Abstract

Garcea G, Berry DP, Jones DJ, Singh R, Dennison AR, Farmer PB, Sharma RA, Steward WP, Gescher AJ.
Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences.

http://www.ncbi.nlm.nih.gov/uids=15668484&dopt=Abstract

Garikapaty VP, Ashok BT, Tadi K, Mittelman A, Tiwari RK.
Synthetic dimer of indole-3-carbinol: second generation diet derived anti-cancer agent in hormone sensitive prostate cancer. Prostate. 2006 Apr 1;66(5):453-62.

http://www.ncbi.nlm.nih.gov/Abstract

Garvin S, Ollinger K, Dabrosin C.
Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo.

http://www.ncbi.nlm.nih.gov/Abstract

Harper CE, Patel BB, Wang J, Arabshahi A, Eltoum IA, Lamartiniere CA.
Resveratrol suppresses prostate cancer progression in transgenic mice.

http://www.ncbi.nlm.nih.gov/Abstract

Hemaiswarya S, Doble M.
Potential synergism of natural products in the treatment of cancer.

http://www.ncbi.nlm.nih.gov/Abstract

Igura K, Ohta T, Kuroda Y, Kaji K.
Resveratrol and quercetin inhibit angiogenesis in vitro.

http://www.ncbi.nlm.nih.gov/uids=11485823&dopt=Abstract

Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM.
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes.

http://www.ncbi.nlm.nih.gov/uids=8985016&dopt=Abstract

Jing XB, Ueki N, Cheng JD, Imanishi H, Hada T
Induction of apoptosis in hepatocellular carcinoma cell lines by emodin

http://www.ncbi.nlm.nih.gov/uids=12716464&dopt=Abstract

Kampa M, Hatzoglou A, Notas G, Damianaki A, Bakogeorgou E, Gemetzi C, Kouroumalis E, Martin PM, Castanas E.
Wine antioxidant polyphenols inhibit the proliferation of human prostate cancer cell lines.

http://www.ncbi.nlm.nih.gov/uids=11142097&dopt=Abstract

Kawamori T, Lubet R, Steele VE, Kelloff GJ, Kaskey RB, Rao CV, Reddy BS.
Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer.

http://www.ncbi.nlm.nih.gov/uids=9973206&dopt=Abstract

Knowles LM, Zigrossi DA, Tauber RA, Hightower C, Milner JA
Flavonoids suppress androgen-independent human prostate tumor proliferation. Nutr Cancer. 2000;38(1):116-22

http://www.ncbi.nlm.nih.gov/Abstract

Maheshwari RK, Singh AK, Gaddipati J, Srimal RC.
Multiple biological activities of curcumin: A short review.

http://www.ncbi.nlm.nih.gov/Abstract

Marambaud P, Zhao H, Davies P.
Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

http://www.ncbi.nlm.nih.gov/Abstract

Martin AR, Villegas I, Sanchez-Hidalgo M, de la Lastra CA.
The effects of resveratrol, a phytoalexin derived from red wines, on chronic inflammation induced in an experimentally induced colitis model.

http://www.ncbi.nlm.nih.gov/Abstract

Olas B, Wachowicz B, Majsterek I, Blasiak J.
Resveratrol may reduce oxidative stress induced by platinum compounds in human plasma, blood platelets and lymphocytes.

http://www.ncbi.nlm.nih.gov/uids=15930895&dopt=Abstract

Pace-Asciak CR, Hahn S, Diamandis EP, Soleas G, Goldberg DM.
The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease.

http://www.ncbi.nlm.nih.gov/Abstract

Palamara AT, Nencioni L, Aquilano K, De Chiara G, Hernandez L, Cozzolino F, Ciriolo MR, Garaci E.
Inhibition of influenza a virus replication by resveratrol.

http://www.ncbi.nlm.nih.gov/uids=15838800&dopt=Abstract

Paul B, Masih I, Deopujari J, Charpentier C.
Occurrence of resveratrol and pterostilbene in age-old darakchasava, an ayurvedic medicine from India.

http://www.ncbi.nlm.nih.gov/uids=10624864&dopt=Abstract

Reddy BS, Rao CV.
Novel approaches for colon cancer prevention by cyclooxygenase-2 inhibitors.

http://www.ncbi.nlm.nih.gov/uids=12171541&dopt=Abstract

Sarkar FH, Li Y.
Indole-3-carbinol and prostate cancer. J Nutr. 2004 Dec;134(12 Suppl):3493S-3498S.

http://www.ncbi.nlm.nih.gov/Abstract

Sasieni P.
Chemoprevention of cervical cancer. Best Pract Res Clin Obstet Gynaecol. 2006 Apr;20(2):295-305. Epub 2006 Jan 4.

http://www.ncbi.nlm.nih.gov/Abstract

Shanmuganayagam D, Beahm MR, Osman HE, Krueger CG, Reed JD, Folts JD.
Grape seed and grape skin extracts elicit a greater antiplatelet effect when used in combination than when used individually in dogs and humans.

http://www.ncbi.nlm.nih.gov/Abstract

Shishodia S, Sethi G, Aggarwal BB.
Curcumin: getting back to the roots.

http://www.ncbi.nlm.nih.gov/Abstract

Soleas GJ, Diamandis EP, Goldberg DM.
Wine as a biological fluid: history, production, and role in disease prevention.

http://www.ncbi.nlm.nih.gov/Abstract

Sovak M.
Grape Extract, Resveratrol, and Its Analogs: A Review.

http://www.ncbi.nlm.nih.gov/uids=12639418&dopt=Abstract

Vigna GB, Costantini F, Aldini G, Carini M, Catapano A, Schena F, Tangerini A, Zanca R, Bombardelli E, Morazzoni P, Mezzetti A, Fellin R, Maffei Facino R.
Effect of a standardized grape seed extract on low-density lipoprotein susceptibility to oxidation in heavy smokers.

http://www.ncbi.nlm.nih.gov/Abstract

Vinson JA, Proch J, Bose P.
MegaNatural((R)) Gold Grapeseed Extract: In Vitro Antioxidant and In Vivo Human Supplementation Studies.

http://www.ncbi.nlm.nih.gov/Abstract

Zern TL, West KL, Fernandez ML.
Grape polyphenols decrease plasma triglycerides and cholesterol accumulation in the aorta of ovariectomized guinea pigs.

http://www.ncbi.nlm.nih.gov/uids=12840191&dopt=Abstract

Zhou HB, Chen JJ, Wang WX, Cai JT, Du Q.
Anticancer activity of resveratrol on implanted human primary gastric carcinoma cells in nude mice.

http://www.ncbi.nlm.nih.gov/uids=15633232&dopt=Abstract

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