Business and Marketing - INTERPHARMA PRAHA, a.s.

Sales team

Head of Business Department

Natalie Ziňkova

e-mail: nzinkova-ZAVINOVADLO:ipp-otsuka.cz

tel.: +420 241 050 328

+420 241 050 328
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Active Pharmaceutical Ingredients

Iohexol

A generic nonionic radiographic contrast agent.

Bulk powder ready for formulation.

DMF and CEP available.

Meetst the latest requirements and specifications of these leading Pharmacopoeias:

EU (Ph. Eur.) and Japan (JPC - Japanese Pharmaceutical Codex)

Iohexol

N,N'-Bis (2,3-dihydroxypropyl)-5-[N- (2,3-dihydroxypropyl)acetamido]-2,4,6-triiodoisophthalamide

Molecular Formula: C19H26I3N3O9

C. A. S. No.: [66108-95-0]

Troxerutin

Synthetically modified rutin with increased solubility in water.

For topical, oral or intravenous use.

For suppression of peripheral venous inflammatory disorders.

DMF available.

Troxerutin

3’,4’,7-Tris[O-(2-hydroxyethyl)]rutin

Molecular Formula: C33H42O19

C.A.S. No.: [7085-55-4]

4-Borono-L-fenylalanin (BPA)

10B enriched 4-Borono-L-phenylalanine (BPA)

A delivery agent of 10B used for treating melanomas and malignant brain tumors by Boron Neutron Capture Therapy (BNCT).

Produced by a novel effective process developed by IPP under GMP, on large commercial scale.

4-Borono-L-fenylalanin (BPA)

4-(Borono 10B) -L-phenylalanine

Molecular Formula: C9H12BNO4

C. A. S. No.: [80994-59-8]

Scientific References:

The Basics of Boron Neutron Capture Therapy: http://web.mit.edu/description.html

 

Coderre JA, Glass JD, Fairchild RG, Micca PL, Fand I, Joel DD: Selective delivery of boron by the melanin precursor analogue p-boronophenylalanine to tumors other than melanoma: http://www.ncbi.nlm.nih.gov/Abstract

 

Soloway AH, Tjarks W, Barnum BA, Rong FG, Barth RF, Codogni IM, Wilson JG: The Chemistry of Neutron Capture Therapy: http://www.ncbi.nlm.nih.gov/Abstract

Trimecain HCl

Local anesthetic.

DMF available.

Trimecain HCl

2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide-hydrochloride

Molecular Formula: C15H25ClN2O

C.A.S. No.: [1027-14-1]

Trospium Chloride

API used for antimuscarinic treatment of overactive bladder (OAB), reduces urinary incontinence.

Produced by a novel improved synthetic technology.

DMF and CEP available.

Trospium Chloride

(1R,3r,5S)-3-[(Hydroxydiphenylacetyl)oxy]spiro[8-azoniabicyclo[3,2,1]octane-8,1´-pyrrolidinium] chloride

Molekulární vzorec: C25H30ClNO3

C.A.S. No.: [10405-02-4]

Dithiaden

Oral antihistamine.

DMF available.

Dithiaden

N, N-dimethyl-3-thieno[2,3-c][2]benzothiepin-4(9H)-ylidenepropylamine hydrochloride

Molekulární vzorec: C17H20ClNS2

C.A.S. No.: [1154-12-7]

Nutraceutical Ingredients

Bioswellix

  • Made from the resin of the Olibanum (or Frankincense) tree (Boswellia serrata), an indian plant used in traditional ayurvedic medicine as anti-inflammatory treatment
  • Standardized to min. 35 % (w/w by HPLC, not just by titration) of the most active acids AKBA and ABA
  • Bioswellix is produced in unique quality by a process patented by Interpharma, in which the content of the two most active compounds AKBA and ABA is enriched
  • Available in bulk

Diindolylmetan

Synthetic 98% diindolylmethane

  • For healthy hormone balance and metabolism
  • DIM (Diindolylmethane) is a powerful ingredient derived from I3C (indole-3-carbinol), the natural precursor found in cruciferous (Brassicaceae) vegetables such as broccoli or cabbage, that balances estrogen metabolism
  • Produced by a unique Interpharma Praha technology and marketed in a capsule formulation by BioResponse Nutrients, LLC (U. S. )
  • DMF filed with FDA
  • Available in bulk

Hepacept®

Purified plant extract composition

  • Liver function support (anti-inflammatory properties)
  • Gastrointestinal protection (anti-inflammatory properties)
  • Made from 6 concentrated and standardized plant extracts used in traditional asian medicines
  • Proven synergistic effect of the plant extract components compared to isolated compounds
  • Contains purified extracts from Knotweed (resveratrol), Olibanum resin (Bioswellix), root of Turmeric (curcumin), seeds of Milk Thistle (silymarin), root of Baical Scullcap (baicalin) and small amount of Black pepper extract (piperin) for increased bioavailability
  • Available in bulk and as a final product in capsules

Regrapex-R® forte

Whole red grape extract with 35% of natural trans-resveratrol complex.

  • Same characteristics as Regrapex-R, but contains more resveratrol
  • Available in bulk

Resveratrol Glycon HP (high purity)

Contains minimum 98% of highly purified trans-resveratrol glucoside.

  • Same characteristics as Resveratrol HP
  • Highly purified, contains min. 98% trans-resveratrol glycon (glucoside) made from the roots of Japanese Knotweed
  • As a glucoside of resveratrol, it has better oral bioavailability and better water solubility. It can be easily formulated into functional drinks
  • Contains no residual solvents other than ethanol (by GC headspace)
  • Available in bulk

Dermocosmetics

Eucapil®

Eucapil® is an original, clinically tested preparation for external use for hair loss treatment.

Eucapil

Eucapil® works through a unique mechanism of hair root protection against the effects of the hormones that cause hair loss in hereditary baldness.

 

Fluridil is a patented active ingredient of Eucapil® developed in the laboratories of Biophysica, Inc. in California. Fluridil works only locally on the scalp. Its excess decomposes into substances with no side effects.

Composition:

Application:

2% solution of fluridil in isopropyl alcohol, 2.5% grape seed oil

1 ampoule per day, apply to dry scalp and massage gently

Packaging: 30 ampoules, each containing 2 ml

Contract Manufacturing

IPP can provide contract manufacturing services in GMP certified manufacturing units:

  • multipurpose full-scale modern unit for API production (batch sizes up to 300 kg)
  • multipurpose low volume unit (batch sizes up to 10 kg)

IPP also offers a full range of services in the development of industrial manufacturing processes, primarily for the production of APIs and intermediates.

Details on contract manufacturing capacities and development services are included in the Contract Manufacturing Capabilities brochure and are also described on the Research and Development site.

Catalogues